The South Atlantic may seem to have been "out of the action" for the war raging in Europe, but that wasn't the case. Nazi German ships attempted to run Allied blockades to get essential war materials. On March 10, 1943, Eberle on patrol encountered one such blockade runner, the Karin. After firing on the enemy ship and forcing her to stop, Eberle dispatched a boarding party. As the Americans boarded the German vessel, the enemy crew detonated demolition charges.
Three of the Americans on the boarding party were decorated with the Navy Cross for their heroism. They were Seaman First Class Alexander J. Bisheimer, Lieutenant Frederick L. Edwards, Jr., and Signalman Third Class William J. Pattison.